Isaac Low, American merchant and politician, founded the New York Chamber of Commerce (d. 1791)

Isaac Low (April 13, 1735 – July 25, 1791) was an American merchant in New York City and a Founding Father of the United States who served as a member of the Continental Congress, where he signed the Continental Association, and he later served as a delegate to the New York Provincial Congress. Though originally a Patriot, he later joined the Loyalist cause in the American Revolution.