At the University of Utah, Barney Clark becomes the first person to receive a permanent artificial heart.

An artificial heart is a device that replaces the heart. Artificial hearts are typically used to bridge the time to heart transplantation, or to permanently replace the heart in the case that a heart transplant (from a deceased human or, experimentally, from a deceased genetically engineered pig) is impossible. Although other similar inventions preceded it from the late 1940s, the first artificial heart to be successfully implanted in a human was the Jarvik-7 in 1982, designed by a team including Willem Johan Kolff, William DeVries and Robert Jarvik.An artificial heart is distinct from a ventricular assist device (VAD; for either one or both of the ventricles, the heart's lower chambers), which can be a permanent solution also, or the intra-aortic balloon pump- both devices are designed to support a failing heart. It is also distinct from a cardiopulmonary bypass machine, which is an external device used to provide the functions of both the heart and lungs, used only for a few hours at a time, most commonly during cardiac surgery. It is also distinct from a ventilator, used to support failing lungs, or the extracorporeal membrane oxygenation (ECMO), which is used to support those with both inadequate heart and lung function for up to days or weeks, unlike the bypass machine.

The University of Utah (U of U, UofU, or simply The U) is a public research university in Salt Lake City, Utah. It is the flagship institution of the Utah System of Higher Education. The university was established in 1850 as the University of Deseret ( (listen)) by the General Assembly of the provisional State of Deseret, making it Utah's oldest institution of higher education. It received its current name in 1892, four years before Utah attained statehood, and moved to its current location in 1900.As of Fall 2019, there were 24,485 undergraduate students and 8,333 graduate students, for an enrollment total of 32,818, making it the second largest public university in the state after Utah Valley University. Graduate studies include the S.J. Quinney College of Law and the School of Medicine, Utah's first medical school. It is a member of the Association of American Universities (AAU) and is classified among "R1: Doctoral Universities – Very high research activity". According to the National Science Foundation, the university received $552 million in research and development funding in 2018, ranking it 45th in the nation. In addition, the university's Honors College has been reviewed among 100 leading national Honors Colleges in the U.S. The university's health care system includes four hospitals, including the University of Utah Hospital and Huntsman Cancer Institute, along with twelve community clinics and specialty centers such as the Moran Eye Center. The university's athletic teams, the Utes, participate in NCAA Division I athletics (FBS for football) as a member of the Pac-12 Conference.

Twenty-two Rhodes Scholars, four Nobel Prize winners, three Turing Award winners, eight MacArthur Fellows, various Pulitzer Prize winners, two astronauts, Gates Cambridge Scholars, and Churchill Scholars have been affiliated with the university as students, researchers, or faculty members in its history.