Ephraim Avigdor Speiser, Ukrainian-American archaeologist and scholar (d. 1965)

Ephraim Avigdor Speiser (January 24, 1902 – June 15, 1965) was a Jewish Polish-born American Assyriologist. He discovered the ancient site of Tepe Gawra in 1927 and supervised its excavation between 1931 and 1938.

Speiser was married to Sue Gimbel Dannenbaum, granddaughter of Charles Gimbel of the Gimbel Brothers. They had two children together, Jean and Joel.