Byzantine Emperor Zeno is forced to flee his capital at Constantinople, and his general, Basiliscus gains control of the empire.

Flavius Zeno (; Greek: Zenon; c. 425 9 April 491) was Eastern Roman emperor from 474 to 475 and again from 476 to 491. Domestic revolts and religious dissension plagued his reign, which nevertheless succeeded to some extent in foreign issues. His reign saw the end of the Western Roman Empire following the deposition of Romulus Augustus and the death of Julius Nepos, but he was credited with contributing much to stabilising the Eastern Empire.

In ecclesiastical history, Zeno is associated with the Henotikon or "instrument of union", promulgated by him and signed by all the Eastern bishops, with the design of solving the monophysite controversy. The Henotikon was widely unpopular and eventually abandoned under Justin I.

This is a list of the Byzantine emperors from the foundation of Constantinople in 330 AD, which marks the conventional start of the Byzantine Empire (or the Eastern Roman Empire), to its fall to the Ottoman Empire in 1453 AD. Only the emperors who were recognized as legitimate rulers and exercised sovereign authority are included, to the exclusion of junior co-emperors (symbasileis) who never attained the status of sole or senior ruler, as well as of the various usurpers or rebels who claimed the imperial title.

The following list starts with Constantine the Great, the first Christian emperor, who rebuilt the city of Byzantium as an imperial capital, Constantinople, and who was regarded by the later emperors as the model ruler. It was under Constantine that the major characteristics of what is considered the Byzantine state emerged: a Roman polity centered at Constantinople and culturally dominated by the Greek East, with Christianity as the state religion.

The Byzantine Empire was the direct legal continuation of the eastern half of the Roman Empire following the division of the Roman Empire in 395. Emperors listed below up to Theodosius I in 395 were sole or joint rulers of the entire Roman Empire. The Western Roman Empire continued until 476. Byzantine emperors considered themselves to be rightful Roman emperors in direct succession from Augustus; the term "Byzantine" was coined by Western historiography only in the 16th century. The use of the title "Roman Emperor" by those ruling from Constantinople was not contested until after the Papal coronation of the Frankish Charlemagne as Holy Roman Emperor (25 December 800), done partly in response to the Byzantine coronation of Empress Irene, whose claim, as a woman, was not recognized by Pope Leo III.

In practice, according to the Hellenistic political system, the Byzantine emperor had been given total power through God to shape the state and its subjects, he was the last authority and legislator of the empire and all his work was in imitation of the sacred kingdom of God, also according to the Christian principles,he was the ultimate benefecator and protector of his people.