Juan de Palafox y Mendoza, Spanish-born bishop and viceroy of New Spain (d. 1659)

Juan de Palafox y Mendoza (26 June 1600 – 1 October 1659) was a Spanish politician, administrator, and Catholic clergyman in 17th century Spain and a viceregal of Mexico.

Palafox was the Bishop of Puebla (1640−1655), and the interim Archbishop of Mexico (1640−1642). He also held political office, from 10 June 1642 to 23 November 1642 as the Viceroy of New Spain. He lost a high-profile struggle with the Jesuits in New Spain, resulting in a recall to Spain, to the minor Diocese of Osma in Old Castile. Although a case was opened for his beatification shortly after he died in 1659, he was not designated "Blessed" until 2011.