In reaction to the Passover massacre two days prior, Israel launches Operation Defensive Shield against Palestinian militants, its largest military operation in the West Bank since the 1967 Six-Day War.

Operation "Defensive Shield" (Hebrew: , Mivtza Homat Magen, literally "Operation Shield Wall") was a large-scale military operation conducted by the Israel Defense Forces in 2002 during the Second Intifada. It was the largest military operation in the West Bank since the 1967 Six-Day War. The stated goal of the operation was to stop terrorist attacks. The operation was a direct response to the Passover massacre on March 27 at the Park Hotel in the Israeli resort city of Netanya when a Palestinian suicide bomber killed 30 vacationers.Operation Defensive Shield began on March 29, 2002, with an incursion into Ramallah placing Yasser Arafat under siege in his Ramallah compound, followed by incursions into the six largest cities in the West Bank, and their surrounding localities. The Israel Defense Forces invaded Tulkarm and Qalqilya on April 1, Bethlehem the next day, Jenin and Nablus the next. From April 321, the period was characterized by strict curfews on civilian populations and restrictions of movement of international personnel, including at times prohibition of entry to humanitarian and medical personnel as well as human rights monitors and journalists.In May 2002, the Israeli troops had pulled out of the Palestinian cities, but maintained cordons of troops around West Bank towns and villages, and continued carrying out raids on Palestinian areas.The UN report on the subject says, "Combatants on both sides conducted themselves in ways that, at times, placed civilians in harm's way. Much of the fighting during Operation "Defensive Shield" occurred in areas heavily populated by civilians and in many cases heavy weaponry was used."

The Passover massacre was a suicide bombing carried out by Hamas at the Park Hotel in Netanya, Israel on 27 March 2002, during a Passover seder. Thirty civilians were killed in the attack and 140 were injured. It was the deadliest attack against Israelis during the Second Intifada.