After the aircraft's departure from Miami, a fire started by improperly handled chemical oxygen generators in the cargo hold of Atlanta-bound ValuJet Flight 592 causes the Douglas DC-9 to crash in the Florida Everglades killing all 110 on board.

ValuJet Airlines Flight 592 was a regularly scheduled flight from Miami International Airport to HartsfieldJackson Atlanta International Airport. On May 11, 1996, the ValuJet Airlines McDonnell Douglas DC-9 operating the route crashed into the Everglades about 10 minutes after taking off from Miami as a result of a fire in the cargo compartment caused by improperly stored and labeled hazardous cargo. All 110 people on board died. The airline already had a poor safety record before the crash, and the accident brought widespread attention to the airline's problems. The airline was grounded for several months after the accident. When operations resumed, ValuJet was unable to attract the same amount of customers that it had before the accident. It acquired AirTran in 1997, but the lingering damage to the ValuJet name led ValuJet executives to assume the AirTran name.

Miami (), officially the City of Miami, is a coastal metropolis located in Miami-Dade County in southeastern Florida (United States). With a population of 442,241 as of the 2020 census, it is the second-most populous city in Florida, eleventh-most populous city in the Southeast, and 44th-most populous city in the United States. Miami is the core of the nation's eighth-largest metropolitan area with 6,138,333 people. The city has the third-largest skyline in the U.S. with over 300 high-rises, 58 of which exceed 491 ft (150 m).Miami is a major center and leader in finance, commerce, culture, arts, and international trade. The metro area is by far the largest urban economy in Florida and the 12th largest in the United States, with a GDP of $344.9 billion as of 2017. In 2020, Miami was classified as a Beta + level global city by the GaWC. In 2019, Miami ranked seventh in the United States and 31st among global cities in business activity, human capital, information exchange, cultural experience, and political engagement. According to a 2018 UBS study of 77 world cities, the city was ranked as the third-richest in the world and the second-richest in the United States in purchasing power. Miami is one of the largest majority-minority cities in the United States and the fourth-largest majority-Hispanic city in the United States, with 70.2% of its population being Hispanic in 2020.Greater Downtown Miami has one of the largest concentrations of international banks in the United States, and is home to many large national and international companies. The Health District, home to Jackson Memorial Hospital and the Leonard M. Miller School of Medicine at the University of Miami and others, is a major center for hospitals, clinics, and the biotechnology and medical research industries. PortMiami is the busiest cruise port in the world in both passenger traffic and cruise lines, and refers to itself as the "Cruise Capital of the World". Miami is also a major tourism hub for international visitors, ranking second in the country after New York City. Miami has been called the Gateway to Latin America.