Births on November 22

Alfonso II d'Este, Duke of Ferrara, Italian noble (d. 1597)

Alfonso II d'Este (24 November 1533 – 27 October 1597) was Duke of Ferrara from 1559 to 1597. He was a member of the House of Este.

23 May

Henry VIII of England
The marriage of King Henry VIII to Catherine of Aragon is declared null and void.
28 May

Thomas Cranmer
The Archbishop of Canterbury, Thomas Cranmer, declares the marriage of King Henry VIII of England to Anne Boleyn valid.