Mexican chemist Luis E. Miramontes conducts the very last step of the first synthesis of norethisterone, the progestin that would later be used in one of the first three oral contraceptives.
The combined oral contraceptive pill (COCP), often referred to as the birth control pill or colloquially as "the pill", is a type of birth control that is designed to be taken orally by women. The pill contains two important hormones: progestin (a synthetic form of the hormone progestogen/progesterone) and estrogen (usually ethinylestradiol and 17 estradiol). When taken correctly, it alters the menstrual cycle to eliminate ovulation and prevent pregnancy.
COCPs were first approved for contraceptive use in the United States in 1960, and are a very popular form of birth control. They are used by more than 100 million women worldwide and by about 9 million women in the United States. From 2015 to 2017, 12.6% of women aged 1549 in the US reported using COCPs, making it the second most common method of contraception in this age range (female sterilization is the most common method). Use of COCPs, however, varies widely by country, age, education, and marital status. For example, one third of women aged 1649 in the United Kingdom currently use either the combined pill or progestogen-only pill (POP), compared with less than 3% of women in Japan (as of 19502014).Combined oral contraceptives are on the World Health Organization's List of Essential Medicines. The pill was a catalyst for the sexual revolution.
Luis Ernesto Miramontes Cárdenas (March 16, 1925 – September 13, 2004) was a Mexican chemist known as the co-inventor of the progestin norethisterone used in one of the first three oral contraceptives.
Miramontes was born in Tepic, Nayarit. He obtained his first Degree in chemical engineering at the Universidad Nacional Autónoma de México (UNAM). He was a founding researcher of the Institute of Chemistry of UNAM, specializing mainly in the area of Organic Chemistry. He was a professor of the Faculty of Chemistry of UNAM, Director and professor of the School of Chemistry at the Universidad Iberoamericana, and deputy Director of Research at the Mexican Institute of Petroleum (IMP). Miramontes was a member of diverse scientific societies, such as the American Chemical Society (Emeritus), the Mexican Institute of Chemical Engineers, the National Institute of Chemical and Chemical Engineers, the Chemical Society of Mexico, the American Institute of Chemical Engineers and the New York Academy of Sciences. He died in Mexico City in 2004.