John Woodruff, American runner and colonel (b. 1915)
John Woodruff may refer to:
John Woodruff (athlete) (1915–2007), American middle-distance runner
John Woodruff (representative) (1826–1868), U.S. Representative from Connecticut
John Woodruff (director) (fl. 2000s–2010s), American actor and director
John I. Woodruff (1864–1962), American football coach and member of the Pennsylvania House of Representatives