The Moby Prince disaster was a major maritime accident resulting in 140 deaths. It occurred in the late evening of Wednesday 10 April 1991, in the harbor of Livorno, Italy. It is the worst disaster in the Italian merchant navy since World War II. It is also considered one of the two worst environmental disasters in Italian history, along with the explosion and loss of the tanker Amoco Milford Haven on the following day in an unrelated accident near Voltri.MV Moby Prince, a ferry owned by Navigazione Arcipelago Maddalenino (NAVARMA) Lines collided with the oil tanker Agip Abruzzo, sparking an extensive fire that ravaged the ship. The only survivor of the crew and passengers of the ferry was a young ship's boy, Alessio Bertrand from Naples. The other 140 on board were killed by the fire or toxic fumes.

On 28 May 1998 the ship's hull sank while impounded in a dock in Leghorn Harbour; it was later refloated and sent to be scrapped in Turkey.