Pope Boniface VIII (Latin: Bonifatius PP. VIII; born Benedetto Caetani, c. 1230 11 October 1303) was the head of the Catholic Church and ruler of the Papal States from 24 December 1294 to his death in 1303. The Caetani family was of baronial origin, with connections to the papacy. He succeeded Pope Celestine V, who had abdicated from the papal throne. Boniface spent his early career abroad in diplomatic roles.

Boniface VIII put forward some of the strongest claims of any pope to temporal as well as spiritual power. He involved himself often with foreign affairs, including in France, Sicily, Italy and the First War of Scottish Independence. These views, and his chronic intervention in "temporal" affairs, led to many bitter quarrels with Albert I of Germany, Philip IV of France, and Dante Alighieri, who placed the pope in the Eighth Circle of Hell in his Divine Comedy, among the simoniacs.

Boniface systematized canon law by collecting it in a new volume, the Liber Sextus (1298), which continues to be important source material for canon lawyers. He established the first Catholic "jubilee" year to take place in Rome. Boniface had first entered into conflict with Philip IV of France in 1296 when the latter sought to reinforce the nascent nation state by imposing taxes on the clergy and barring them from administration of the law. Boniface excommunicated Philip and all others who prevented French clergy from traveling to the Holy See, after which the king sent his troops to attack the pope's residence in Anagni on 7 September 1303 and capture him. Boniface was held for three days and beaten badly.

King Philip IV pressured Pope Clement V of the Avignon Papacy into staging a posthumous trial of Boniface. He was accused of heresy and sodomy, but no verdict against him was delivered.

The Sapienza University of Rome (Italian: Sapienza – Università di Roma), also called simply Sapienza or the University of Rome, and formally the Università degli Studi di Roma "La Sapienza", is a public research university located in Rome, Italy. It is one of the largest European universities by enrollments and one of the oldest in history, founded in 1303. The university is one of the most prestigious Italian universities and in the world, commonly ranking first in national rankings and in Southern Europe. In 2018, 2019 and 2021 it ranked first in the world for classics and ancient history.Most of the Italian ruling class studied at the Sapienza. The Sapienza educated numerous notable alumni, including many Nobel laureates, Presidents of the European Parliament and European Commissioners, heads of several nations, notable religious figures, scientists and astronauts. In September 2018, it was included in the top 100 of the QS World University Rankings Graduate Employability Ranking.