The Rhythm Club fire (or The Natchez Dance Hall Holocaust) was a fire in a dance hall in Natchez, Mississippi on the night of April 23, 1940, which killed 209 people and severely injured many others. Hundreds of people were trapped inside the building. At the time, it was the second deadliest building fire in the history of the nation. It is now ranked as the fourth deadliest assembly and club fire in U.S. history.