Francis Lee, English footballer and businessman
Francis Lee may refer to:

Francis Lee (director), English actor and film director of God's Own Country

Francis Lee (footballer), former professional footballer.

Francis Lee (physician) (1661–1719), English writer known for his connection with the Philadelphians

Blair Lee I (Francis Preston Blair Lee, 1857–1944), Democratic member of the United States Senate

Francis Joseph Lee (1857–1909), chess player

Francis Lightfoot Lee (1734–1797), signer of the United States Declaration of Independence

SS Francis L. Lee, a Liberty ship

Francis Nigel Lee (1934–2011), Christian theologian

Francis D. Lee (1826–1885), American architect from Charleston, South Carolina

Francis Lee (lyricist), contemporary Chinese-pop lyricist, writer

Francis F. Lee (born 1927), inventor, entrepreneur, and professor of electrical engineering and computer science

Sir Francis Lee, 4th Baronet (1639–1667), English politician