The Edict of Nantes (French: dit de Nantes) was signed in April 1598 by King Henry IV and granted the Calvinist Protestants of France, also known as Huguenots, substantial rights in the nation, which was in essence completely Catholic. In the edict, Henry aimed primarily to promote civil unity. The edict separated civil from religious unity, treated some Protestants for the first time as more than mere schismatics and heretics and opened a path for secularism and tolerance. In offering a general freedom of conscience to individuals, the edict offered many specific concessions to the Protestants, such as amnesty and the reinstatement of their civil rights, including the right to work in any field, even for the state, and to bring grievances directly to the king. It marked the end of the French Wars of Religion, which had afflicted France during the second half of the 16th century.

The Edict of St. Germain, promulgated 36 years earlier by Catherine de Mdici, had granted limited tolerance to Huguenots but was overtaken by events, as it was not formally registered until after the Massacre of Vassy on 1 March 1562, which triggered the first of the French Wars of Religion.

The Edict of Fontainebleau, which revoked the Edict of Nantes in October 1685, was promulgated by Louis XIV, the grandson of Henry IV. This act drove an exodus of Protestants and increased the hostility of Protestant nations bordering France.

Henry IV (French: Henri IV; 13 December 1553 – 14 May 1610), also known by the epithet Good King Henry or Henry the Great, was King of Navarre (as Henry III) from 1572 and King of France from 1589 to 1610. He was the first monarch of France from the House of Bourbon, a cadet branch of the Capetian dynasty. He was assassinated in 1610 by François Ravaillac, a Catholic zealot, and was succeeded by his son Louis XIII.

The son of Antoine de Bourbon, Duke of Vendôme and Jeanne d'Albret, the Queen of Navarre, Henry was baptised as a Catholic but raised in the Protestant faith by his mother. He inherited the throne of Navarre in 1572 on his mother's death. As a Huguenot, Henry was involved in the French Wars of Religion, barely escaping assassination in the St. Bartholomew's Day massacre. He later led Protestant forces against the royal army.

Henry and his predecessor Henry III of France were direct descendants of King Louis IX. Henry III belonged to the House of Valois, descended from Philip III of France, elder son of Saint Louis; Henry IV belonged to the House of Bourbon, descended from Robert, Count of Clermont, younger son of Saint Louis. As Head of the House of Bourbon, Henry was "first prince of the blood". Upon the death of his brother-in-law and distant cousin Henry III in 1589, Henry was called to the French succession by the Salic law.

He initially kept the Protestant faith (the only French king to do so) and had to fight against the Catholic League, which denied that he could wear France's crown as a Protestant. After four years of stalemate, he converted to Catholicism to obtain mastery over his kingdom (reportedly saying, "Paris is well worth a mass"). As a pragmatic politician (in the parlance of the time, a politique), he promulgated the Edict of Nantes (1598), which guaranteed religious liberties to Protestants, thereby effectively ending the French Wars of Religion.

An active ruler, Henry worked to regularise state finance, promote agriculture, eliminate corruption and encourage education. During his reign, the French colonization of the Americas truly began with the foundation of the colonies of Acadia and Canada at Port-Royal and Quebec, respectively. He is celebrated in the popular song "Vive le roi Henri" (which later became an anthem for the French monarchy during the reigns of his successors) and in Voltaire's Henriade.