Operation Babylift was the name given to the mass evacuation of children from South Vietnam to the United States and other western countries (including Australia, France, West Germany, and Canada) at the end of the Vietnam War (see also the Fall of Saigon), on April 326, 1975. By the final American flight out of South Vietnam, over 3,300 infants and children had been evacuated, although the actual number has been variously reported. Along with Operation New Life, over 110,000 refugees were evacuated from South Vietnam at the end of the Vietnam War. Thousands of children were airlifted from Vietnam and adopted by families around the world.

The Lockheed C-5 Galaxy is a large military transport aircraft designed and built by Lockheed, and now maintained and upgraded by its successor, Lockheed Martin. It provides the United States Air Force (USAF) with a heavy intercontinental-range strategic airlift capability, one that can carry outsized and oversized loads, including all air-certifiable cargo. The Galaxy has many similarities to the smaller Lockheed C-141 Starlifter and the later Boeing C-17 Globemaster III. The C-5 is among the largest military aircraft in the world.

The C-5 Galaxy's development was complicated, including significant cost overruns, and Lockheed suffered significant financial difficulties. Shortly after entering service, cracks in the wings of many aircraft were discovered and the C-5 fleet was restricted in capability until corrective work was completed. The C-5M Super Galaxy is an upgraded version with new engines and modernized avionics designed to extend its service life to 2040 and beyond.

The USAF has operated the C-5 since 1969. In that time, the airlifter supported US military operations in all major conflicts including Vietnam, Iraq, Yugoslavia, and Afghanistan, as well as allied support, such as Israel during the Yom Kippur War and operations in the Gulf War. The Galaxy has also distributed humanitarian aid, provided disaster relief, and supported the US space program.