George III, Prince of Anhalt-Dessau, German prince (d. 1553)
George III, Prince of Anhalt-Dessau (Dessau, 15 August 1507 – Dessau, 17 October 1553), was a German prince of the House of Ascania and ruler of the principality of Anhalt-Dessau, and also a Protestant Reformer. After 1544 he became the first ruler of the principality of Anhalt-Plötzkau.

George was the third (but second surviving) son of Ernest I, Prince of Anhalt-Dessau, by his wife Margarete, daughter of Henry I, Duke of Münsterberg-Oels and granddaughter of George of Poděbrady, King of Bohemia.