John Claypole, English politician (d. 1688)
John Claypole (21 August 1625 – 26 June 1688) was an officer in the Parliamentary army in 1645 during the English Civil War. He was created Lord Claypole by Oliver Cromwell, but this title naturally came to an end with the Restoration of 1660.

Claypole married Elizabeth, Oliver Cromwell's second daughter, before October 1646, and raised a troop of horse for Parliament to oppose Charles II in 1651. He was master of the horse to his father-in-law the Lord Protector. A Member of Parliament in 1654 and 1656, he was one of Cromwell's peers in 1657. After the restoration of the monarchy he lived quietly, but may have been briefly imprisoned as a suspect in a plot in 1678, only to be released when no evidence of his involvement was presented.