Eastern Air Lines Flight 401 was a scheduled flight from New York JFK to Miami. Shortly before midnight on December 29, 1972, the Lockheed L-1011-1 TriStar crashed into the Florida Everglades, causing 101 fatalities. All three cockpit crew members, two of the 10 flight attendants, and 96 of the 163 passengers were killed; there were 75 survivors.

The crash occurred while the entire cockpit crew was preoccupied with a burnt-out landing gear indicator light. They failed to notice that the autopilot had inadvertently been disconnected, and as a result, the aircraft gradually lost altitude and crashed. This was the first fatal crash of a wide-body aircraft. It was also the first hull loss and first fatal crash of a Lockheed L-1011 TriStar.