Bob Casale, American guitarist, keyboard player, and producer (b. 1952)
Robert Edward "Bob" Casale, Jr. (born Robert Edward Pizzute, Jr.; July 14, 1952 – February 17, 2014), or "Bob 2", was an American multi-instrumentalist, composer, record producer and audio engineer.

Casale's music career spanned more than 40 years. He came to prominence in the late 1970s as the keyboardist and rhythm guitarist of the new wave band Devo, which released a Top 20 hit in 1980 with the single "Whip It". The band has maintained a cult following throughout its existence. He was the younger brother of their co-founder and bass guitarist Gerald Casale.