Hagia Sophia (Turkish: Ayasofya; Koin Greek: , romanized: Haga Sopha; Latin: Sancta Sophia, lit.'Holy Wisdom',(Turkish: Ayasofya-i) and formerly as the Church of Holy Wisdom (Greek: , romanized: Nas tis Ayas tou Theo Sofas), is a Late Antique place of worship in Istanbul, designed by the Greek geometers Isidore of Miletus and Anthemius of Tralles. Built in 537 as the patriarchal cathedral of the imperial capital of Constantinople, it was the largest Christian church of the eastern Roman Empire (the Byzantine Empire) and the Eastern Orthodox Church, except during the Latin Empire from 1204 to 1261, when it temporarily became a Roman Catholic cathedral. In 1453, after the Fall of Constantinople to the Ottoman Empire, it was converted into a mosque. In 1935, the Republic of Turkey established it as a museum. In 2020, it was reconverted into a mosque.

Built by the eastern Roman emperor Justinian I as the Christian cathedral of Constantinople for the state church of the Roman Empire between 532 and 537, the church was then the world's largest interior space and among the first to employ a fully pendentive dome. It is considered the epitome of Byzantine architecture and is said to have "changed the history of architecture". The present Justinianic building was the third church of the same name to occupy the site, as the prior one had been destroyed in the Nika riots. As the episcopal see of the ecumenical patriarch of Constantinople, it remained the world's largest cathedral for nearly a thousand years, until Seville Cathedral was completed in 1520. Beginning with subsequent Byzantine architecture, Hagia Sophia became the paradigmatic Orthodox church form, and its architectural style was emulated by Ottoman mosques a thousand years later. It has been described as "holding a unique position in the Christian world" and as an architectural and cultural icon of Byzantine and Eastern Orthodox civilization.The religious and spiritual centre of the Eastern Orthodox Church for nearly one thousand years, the church was dedicated to the Holy Wisdom. It was where the excommunication of Patriarch Michael I Cerularius was officially delivered by Humbert of Silva Candida, the envoy of Pope Leo IX in 1054, an act considered the start of the EastWest Schism. In 1204, it was converted during the Fourth Crusade into a Catholic cathedral under the Latin Empire, before being returned to the Eastern Orthodox Church upon the restoration of the Byzantine Empire in 1261. The doge of Venice who led the Fourth Crusade and the 1204 Sack of Constantinople, Enrico Dandolo, was buried in the church.

After the Fall of Constantinople to the Ottoman Empire in 1453, it was converted to a mosque by Mehmed the Conqueror and became the principal mosque of Istanbul until the 1616 construction of the Sultan Ahmed Mosque. Upon its conversion, the bells, altar, iconostasis, ambo, and baptistery were removed, while iconography, such as the mosaic depictions of Jesus, Mary, Christian saints and angels were removed or plastered over. Islamic architectural additions included four minarets, a minbar and a mihrab. The Byzantine architecture of the Hagia Sophia served as inspiration for many other religious buildings including the Hagia Sophia in Thessaloniki, Panagia Ekatontapiliani, the ehzade Mosque, the Sleymaniye Mosque, the Rstem Pasha Mosque and the Kl Ali Pasha Complex. The patriarchate moved to the Church of the Holy Apostles, which became the city's cathedral.

The complex remained a mosque until 1931, when it was closed to the public for four years. It was re-opened in 1935 as a museum under the secular Republic of Turkey, and the building was Turkey's most visited tourist attraction in 2015 and 2019.

In July 2020, the Council of State annulled the 1934 decision to establish the museum, and the Hagia Sophia was reclassified as a mosque. The 1934 decree was ruled to be unlawful under both Ottoman and Turkish law as Hagia Sophia's waqf, endowed by Sultan Mehmed, had designated the site a mosque; proponents of the decision argued the Hagia Sophia was the personal property of the sultan. This redesignation drew condemnation from the Turkish opposition, UNESCO, the World Council of Churches, the International Association of Byzantine Studies, and many international leaders.

This is a list of the Byzantine emperors from the foundation of Constantinople in 330 AD, which marks the conventional start of the Byzantine Empire (or the Eastern Roman Empire), to its fall to the Ottoman Empire in 1453 AD. Only the emperors who were recognized as legitimate rulers and exercised sovereign authority are included, to the exclusion of junior co-emperors (symbasileis) who never attained the status of sole or senior ruler, as well as of the various usurpers or rebels who claimed the imperial title.

The following list starts with Constantine the Great, the first Christian emperor, who rebuilt the city of Byzantium as an imperial capital, Constantinople, and who was regarded by the later emperors as the model ruler. It was under Constantine that the major characteristics of what is considered the Byzantine state emerged: a Roman polity centered at Constantinople and culturally dominated by the Greek East, with Christianity as the state religion.

The Byzantine Empire was the direct legal continuation of the eastern half of the Roman Empire following the division of the Roman Empire in 395. Emperors listed below up to Theodosius I in 395 were sole or joint rulers of the entire Roman Empire. The Western Roman Empire continued until 476. Byzantine emperors considered themselves to be rightful Roman emperors in direct succession from Augustus; the term "Byzantine" was coined by Western historiography only in the 16th century. The use of the title "Roman Emperor" by those ruling from Constantinople was not contested until after the Papal coronation of the Frankish Charlemagne as Holy Roman Emperor (25 December 800), done partly in response to the Byzantine coronation of Empress Irene, whose claim, as a woman, was not recognized by Pope Leo III.

In practice, according to the Hellenistic political system, the Byzantine emperor had been given total power through God to shape the state and its subjects, he was the last authority and legislator of the empire and all his work was in imitation of the sacred kingdom of God, also according to the Christian principles,he was the ultimate benefecator and protector of his people.