Cosimo II de' Medici, Grand Duke of Tuscany (b. 1590)
Cosimo II de' Medici (12 May 1590 – 28 February 1621) was Grand Duke of Tuscany from 1609 until his death. He was the elder son of Ferdinando I de' Medici, Grand Duke of Tuscany, and Christina of Lorraine.
For the majority of his twelve-year reign, he delegated the administration of Tuscany to his ministers. He is best remembered as the patron of Galileo Galilei, his childhood tutor.

1621Feb, 28
Cosimo II de' Medici, Grand Duke of Tuscany
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Events on 1621
- 17Feb
Plymouth Colony
Myles Standish is appointed as first military commander of the English Plymouth Colony in North America. - 16Mar
Plymouth Colony
Samoset, a Mohegan, visited the settlers of Plymouth Colony and greets them, "Welcome, Englishmen! My name is Samoset." - 22Mar
Wampanoag people
The Pilgrims of Plymouth Colony sign a peace treaty with Massasoit of the Wampanoags. - 21Jun
Battle of White Mountain
Execution of 27 Czech noblemen on the Old Town Square in Prague as a consequence of the Battle of White Mountain.