Isabella, Duchess of Lorraine (b. 1400)
Isabella (1400 – 28 February 1453) was suo jure Duchess of Lorraine, from 25 January 1431 to her death in 1453. She was also Queen of Naples by marriage to René of Anjou. Isabella ruled the Kingdom of Naples and her husband's domains in France as regent during his imprisonment in Burgundy in 1435-1438.