STS-63 was the second mission of the US/Russian Shuttle-Mir Program, which carried out the first rendezvous of the American Space Shuttle with Russia's space station Mir. Known as the 'Near-Mir' mission, the flight used Space Shuttle Discovery, which lifted off from launch pad 39B on 3 February 1995 from Kennedy Space Center, Florida. A night launch and the 20th mission for Discovery, it marked the first time a Space Shuttle mission had a female pilot, Eileen Collins, and the first EVAs for both a UK born astronaut, Michael Foale, and a US astronaut of African heritage, Bernard A. Harris, Jr. It also carried out the successful deployment and retrieval of the Spartan-204 platform, along with the scheduled rendezvous and flyaround of Mir, in preparation for STS-71, the first mission to dock with Mir.

Eileen Marie Collins (born November 19, 1956) is a retired NASA astronaut and United States Air Force colonel. A former military instructor and test pilot, Collins was the first female pilot and first female commander of a Space Shuttle. She was awarded several medals for her work. Colonel Collins has logged 38 days 8 hours and 20 minutes in outer space. Collins retired on May 1, 2006, to pursue private interests, including service as a board member of USAA.