The Palestine Liberation Organization (PLO; Arabic: , Munaamat at-Tarr al-Filasniyyah) is a Palestinian nationalist political and militant organization founded in 1964 with the initial purpose of establishing Arab unity and statehood over the territory of former Mandatory Palestine, in opposition to the State of Israel. In 1993, alongside the Oslo I Accord, the PLO's aspiration for Arab statehood was revised to be specifically for the Palestinian territories under an Israeli occupation since the 1967 ArabIsraeli War. It is headquartered in the city of Al-Bireh in the West Bank, and is recognized as the sole legitimate representative of the Palestinian people by over 100 countries that it has diplomatic relations with. As the official recognized government of the de jure State of Palestine, it has enjoyed observer status at the United Nations (UN) since 1974. Due to its militant activities, including acts of violence primarily aimed at Israeli civilians, the PLO was designated as a terrorist organization by the United States in 1987, although a later presidential waiver has permitted American contact with the organization since 1988. In 1993, the PLO recognized Israel's right to exist in peace, accepted Resolution 242 of the United Nations Security Council, and rejected "violence and terrorism". In response, Israel officially recognized the PLO as a legitimate authority representing the Palestinian people. However, despite its participation in the Oslo Accords, the PLO continued to employ tactics of violence in the following years, particularly during the Second Intifada of 20002005. On 29 October 2018, the Palestinian Central Council suspended the Palestinian recognition of Israel, and subsequently halted all forms of security and economic cooperation with it.

Mohammed Abdel Rahman Abdel Raouf al-Qudwa al-Husseini (4 / 24 August 1929 – 11 November 2004), popularly known as Yasser Arafat ( ARR-ə-fat, also US: AR-ə-FAHT; Arabic: محمد ياسر عبد الرحمن عبد الرؤوف عرفات القدوة الحسيني‎; Arabic: ياسر عرفات, romanized: Yāsir ʿArafāt) or by his kunya Abu Ammar (Arabic: أبو عمار, romanized: ʾAbū ʿAmmār), was a Palestinian political leader. He was Chairman of the Palestine Liberation Organization (PLO) from 1969 to 2004 and President of the Palestinian National Authority (PNA) from 1994 to 2004. Ideologically an Arab nationalist, he was a founding member of the Fatah political party, which he led from 1959 until 2004.

Arafat was born to Palestinian parents in Cairo, Egypt, where he spent most of his youth and studied at the University of King Fuad I. While a student, he embraced Arab nationalist and anti-Zionist ideas. Opposed to the 1948 creation of the State of Israel, he fought alongside the Muslim Brotherhood during the 1948 Arab–Israeli War. Returning to Cairo, he served as president of the General Union of Palestinian Students from 1952 to 1956. In the latter part of the 1950s he co-founded Fatah, a paramilitary organisation seeking the removal of Israel and its replacement with a Palestinian state. Fatah operated within several Arab countries, from where it launched attacks on Israeli targets. In the latter part of the 1960s Arafat's profile grew; in 1967 he joined the PLO and in 1969 was elected chair of the Palestinian National Council (PNC). Fatah's growing presence in Jordan resulted in military clashes with King Hussein's Jordanian government and in the early 1970s it relocated to Lebanon. There, Fatah assisted the Lebanese National Movement during the Lebanese Civil War and continued its attacks on Israel, resulting in it becoming a major target of Israel's 1978 and 1982 invasions.

From 1983 to 1993, Arafat based himself in Tunisia, and began to shift his approach from open conflict with the Israelis to negotiation. In 1988, he acknowledged Israel's right to exist and sought a two-state solution to the Israeli–Palestinian conflict. In 1994 he returned to Palestine, settling in Gaza City and promoting self-governance for the Palestinian territories. He engaged in a series of negotiations with the Israeli government to end the conflict between it and the PLO. These included the Madrid Conference of 1991, the 1993 Oslo Accords and the 2000 Camp David Summit. In 1994, Arafat received the Nobel Peace Prize, together with Yitzhak Rabin and Shimon Peres, for the negotiations in Oslo. At the time, Fatah's support among the Palestinians declined with the growth of Hamas and other militant rivals. In late 2004, after effectively being confined within his Ramallah compound for over two years by the Israeli army, Arafat fell into a coma and died. While the cause of Arafat's death has remained the subject of speculation, investigations by Russian and French teams determined no foul play was involved.Arafat remains a controversial figure. Palestinians generally view him as a martyr who symbolized the national aspirations of his people. Israelis regarded him as a terrorist. Palestinian rivals, including Islamists and several PLO leftists, frequently denounced him as corrupt or too submissive in his concessions to the Israeli government.