Pierre S. du Pont, American businessman and philanthropist (d. 1954)
Pierre Samuel du Pont (; January 15, 1870 – April 4, 1954) was an American entrepreneur, businessman, philanthropist and member of the prominent du Pont family.

He was president of DuPont from 1915 to 1919, and served on its board of directors until 1940. He also managed General Motors from 1915 to 1920, became GM's president in 1920, and served on GM's board of directors until 1928. Among other notable accomplishments, he was among the founding board of directors of the Empire State Building which opened in 1931.