Francis I (French: Franois Ier; Middle French: Francoys; 12 September 1494 31 March 1547) was King of France from 1515 until his death in 1547. He was the son of Charles, Count of Angoulme, and Louise of Savoy. He succeeded his first cousin once removed and father-in-law Louis XII, who died without a son.

A prodigious patron of the arts, he promoted the emergent French Renaissance by attracting many Italian artists to work for him, including Leonardo da Vinci, who brought the Mona Lisa with him, which Francis had acquired. Francis' reign saw important cultural changes with the growth of central power in France, the spread of humanism and Protestantism, and the beginning of French exploration of the New World. Jacques Cartier and others claimed lands in the Americas for France and paved the way for the expansion of the first French colonial empire.

For his role in the development and promotion of the French language, he became known as le Pre et Restaurateur des Lettres (the 'Father and Restorer of Letters'). He was also known as Franois au Grand Nez ('Francis of the Large Nose'), the Grand Colas, and the Roi-Chevalier (the 'Knight-King') for his personal involvement in the wars against his great rival Emperor Charles V, who was also King of Spain.

Following the policy of his predecessors, Francis continued the Italian Wars. The succession of Charles V to the Burgundian Netherlands, the throne of Spain, and his subsequent election as Holy Roman Emperor, meant that France was geographically encircled by the Habsburg monarchy. In his struggle against Imperial hegemony, Francis sought the support of Henry VIII of England at the Field of the Cloth of Gold. When this was unsuccessful, he formed a Franco-Ottoman alliance with the Muslim sultan Suleiman the Magnificent, a controversial move for a Christian king at the time.

The accession of the King of France to the royal throne was legitimized by a ceremony performed with the Crown of Charlemagne at Notre-Dame de Reims. In late medieval and early modern times, the new king did not need to be anointed in order to be recognized as French monarch but ascended upon the previous monarch's death with the proclamation "Le Roi est mort, vive le Roi!"The most important part of the French ceremony was not the coronation itself, but the Sacre – the anointing or unction of the king. The Carolingian king Pepin the Short was anointed in Soissons (752) to legitimize the accession of the new dynasty. A second anointing of Pepin by Pope Stephen II took place at the Basilica of St Denis in 754, the first to be performed by a Pope. The unction served as a reminder of the baptism of king Clovis I in Reims by archbishop Saint Remi in 496/499, where the ceremony was finally transferred in 816 and completed with the use of the Holy Ampulla found in 869 in the grave of the Saint. Since this Roman glass vial containing the balm due to be mixed with chrism, was allegedly brought by the dove of the Holy Spirit, the French monarchs claimed to receive their power by divine right. Out of respect for the miraculous oil, the king's shirt and the gloves put on after the unction of the hands were burned after the ceremony. Exceptionally, the shirt worn by Louis XV was not burned. The shirt was donated to the King of Portugal, John V, and is today at the National Palace of Mafra, guarded by the Royal and Venerable Confraternity of the Most Blessed Sacrament of Mafra.The coronation regalia like the throne and sceptre of Dagobert I or crown and sword of Charlemagne were kept in the Basilica of Saint-Denis near Paris and the liturgical instruments in Reims like the Holy Ampulla and Chalice, where they are still partly preserved as well as in the Louvre and other Parisians museums.

The Holy Ampulla was kept in a reliquary in the form of a round gold plaque thickly set with jewels in the center of which was a white enamelled representation of the dove of the Holy Spirit, upright with the wings open and pointing down, of which the Holy Ampulla itself formed the body. The reliquary had a heavy chain by which it could be worn around the neck of the abbot of the Abbey of Saint-Remi (where it was normally kept) when he brought it, walking barefoot at the head of a procession of his monks under a canopy carried by four noblemen on horseback, the Hostages of the Holy Ampulla, from the Abbey to the very steps of the high altar of the Cathedral, where he turned the relic over to the Archbishop of Rheims for its use in the coronation ritual. All succeeding Kings of France were anointed with this same oil—mixed with chrism prior to their coronation.French queens were crowned either together with their husband at Reims or alone at Sainte-Chapelle or Abbey of St. Denis.