The Prince of Ning rebellion (Chinese: ) was a rebellion that took place in China between 10 July and 20 August 1519 during the Ming dynasty. It was started by Zhu Chenhao, Prince of Ning and a fifth-generation descendant of Zhu Quan, and was aimed at overthrowing the Zhengde Emperor. The Prince of Ning revolt was one of two princedom rebellions during the Zhengde Emperor's reign; it was preceded by the Prince of Anhua rebellion in 1510.

Zhu Chenhao (Chinese: 朱宸濠; 1 July 1476 – 12 January 1521), or Prince of Ning (寜王), art name Weitian (畏天), was a member of the Ming dynasty's imperial family. He was the 5th generation descendant of Zhu Quan, the 17th son of the Hongwu Emperor. He attempted to usurp the throne and was the leader of the Prince of Ning rebellion.