The Greek junta or Regime of the Colonels was a right-wing military dictatorship that ruled Greece from 1967 to 1974. On 21 April 1967, a group of colonels overthrew the caretaker government a month before scheduled elections which Georgios Papandreou's Centre Union was favoured to win. The dictatorship was characterised by right-wing cultural policies, anti-communism, restrictions on civil liberties, and the imprisonment, torture, and exile of political opponents. It was ruled by Georgios Papadopoulos from 1967 to 1973, but an attempt to renew its support in a 1973 referendum on the monarchy and gradual democratisation was ended by another coup by the hardliner Dimitrios Ioannidis, who ruled it until it fell on 24 July 1974 under the pressure of the Turkish invasion of Cyprus, leading to the Metapolitefsi ("regime change") to democracy and the establishment of the Third Hellenic Republic.

The prime minister of the Hellenic Republic (Greek: Πρωθυπουργός της Ελληνικής Δημοκρατίας, romanized: Prothypourgós tis Ellinikís Dimokratías), colloquially referred to as the prime minister of Greece (Greek: Πρωθυπουργός της Ελλάδας, romanized: Prothypourgós tis Elládas), is the head of government of the Hellenic Republic and the leader of the Greek Cabinet. The incumbent prime minister is Kyriakos Mitsotakis, who took office on 8 July 2019.

The officeholder's official seat (but not residence) is the Maximos Mansion in the centre of Athens. The office is described in the Constitution either as Prime Minister or President of the Government (Πρόεδρος της Κυβερνήσεως). This is the reason why the prime minister is also addressed as "Mr. President".