The George Jackson Brigade was a revolutionary group founded in the mid-1970s, based in Seattle, Washington, and named after George Jackson, a dissident prisoner and Black Panther member shot and killed during an alleged escape attempt at San Quentin Prison in 1971.

The group combined veterans of the women's liberation movement, homosexuals and Black prisoners.

The organization was ideologically diverse, consisting of both communists and anarchists. It engaged in a number of bombings and other attacks on governmental and business sites, as well as bank robberies over the years from 1975 through 1977. The group broke up with the death or imprisonment of many of its members by the end of that period.