Bernard Babior, American physician and biochemist (b. 1935)
Bernard Macy Babior (November 10, 1935 – June 29, 2004) was an American physician and research biochemist.
Born in Los Angeles, he received his M.D. degree at the University of California, San Francisco . After interning at Peter Bent Brigham Hospital, he joined the laboratory of Konrad Bloch at Harvard University and was awarded a Ph.D. degree in 1965. He received further training at The National Institutes of Health, Harvard University and Tufts University. In 1986 he moved to California as staff physician at Scripps Clinic, and Head of the Division of Biochemistry at The Scripps Research Institute.
Early in his career, while studying a vitamin B12-dependent enzyme, Babior recognized that free radicals might play an important role in biologic processes. He showed that the highly reactive oxygen derivative, superoxide was produced by white blood cell NADPH oxidase as a mechanism to kill invading bacteria. As such, Babior was able to explain the etiology of a rare genetic highly fatal immunodeficiency disease, Chronic granulomatous disease, whereby patients are unable to fight off normally non-pathogenic bacteria. Babior and others showed that the very weapons that the body makes to protect itself against microbial invasion can also play an important role in a variety of common diseases, including arthritis, arteriosclerosis, and Alzheimer's disease.
Babior received numerous honors, including membership of the American Society for Clinical Investigation. He was also a Fellow of the American Association for the Advancement of Science. In 1999 he was elected to membership in the National Academy of Sciences, one of the very few physicians practicing medicine to achieve this honor. The same year, he was elected a Fellow of the American Academy of Arts and Sciences.He served on the editorial boards of a number of academic journals, including the Journal of Clinical Investigation, Blood and the Journal of Biological Chemistry. He published more than 250 scientific papers and wrote or edited four books.
Babior died in San Diego after a battle with prostate cancer at the age of sixty-eight. He is survived by his wife, Shirley, and two children, Gregory and Jill.
2004Jun, 29
Bernard Babior
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- 1Jan
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In a vote of confidence, General Pervez Musharraf wins 658 out of 1,170 votes in the Electoral College of Pakistan, and according to Article 41(8) of the Constitution of Pakistan, is "deemed to be elected" to the office of President until October 2007. - 2Feb
Roger Federer
Swiss tennis player Roger Federer becomes the No. 1 ranked men's singles player, a position he will hold for a record 237 weeks. - 1May
European Union
Cyprus, Czech Republic, Estonia, Hungary, Latvia, Lithuania, Malta, Poland, Slovakia, and Slovenia join the European Union, celebrated at the residence of the Irish President in Dublin. - 26May
Oklahoma City bombing
United States Army veteran Terry Nichols is found guilty of 161 state murder charges for helping carry out the Oklahoma City bombing. - 3Aug
September 11 attacks
The pedestal of the Statue of Liberty reopens after being closed since the September 11 attacks.