James E. Webb, American colonel and politician, 16th Under Secretary of State (b. 1906)
James Edwin Webb (October 7, 1906 – March 27, 1992) was an American government official who served as Undersecretary of State from 1949 to 1952. He was also the second appointed administrator of NASA from February 14, 1961, to October 7, 1968. Webb oversaw NASA from the beginning of the Kennedy administration through the end of the Johnson administration, thus overseeing each of the critical first crewed missions throughout the Mercury and Gemini programs until days before the launch of the first Apollo mission. He also dealt with the Apollo 1 fire.

In 2002, the Next Generation Space Telescope (NGST) was renamed the James Webb Space Telescope as a tribute to Webb.