The Treaty of Florence (28 March 1801), which followed the Armistice of Foligno (9 February 1801), brought to an end the war between the French Republic and the Kingdom of Naples, one of the Wars of the French Revolution. Forced by the French military presence, Naples ceded some territories in the Tyrrhenian Sea and accepted French garrisons to their ports on the Adriatic Sea. All Neapolitan harbours were closed to British and Ottoman vessels.

Napoleon was relatively lenient to the defenseless kingdom of Naples thanks to his need to appease Tsar Paul I of Russia and its allies of the League of Neutrals. The Tsar, who was assassinated less than a week before the signing of the treaty, was concerned with the French advance in Italy and had decided to support the King of Naples. The First Consul, wanting to attract the Tsar to his side in the strife in Europe, was forced to allow Ferdinand IV to remain on the throne, albeit now a vassal of Napoleonic France.