Apollo 9 (March 313, 1969) was the third human spaceflight in NASA's Apollo program. Flown in low Earth orbit, it was the second crewed Apollo mission that the United States launched via a Saturn V rocket, and was the first flight of the full Apollo spacecraft: the command and service module (CSM) with the Lunar Module (LM). The mission was flown to qualify the LM for lunar orbit operations in preparation for the first Moon landing by demonstrating its descent and ascent propulsion systems, showing that its crew could fly it independently, then rendezvous and dock with the CSM again, as would be required for the first crewed lunar landing. Other objectives of the flight included firing the LM descent engine to propel the spacecraft stack as a backup mode (as would be required on the Apollo 13 mission), and use of the portable life support system backpack outside the LM cabin.

The three-man crew consisted of Commander James McDivitt, Command Module Pilot David Scott, and Lunar Module Pilot Rusty Schweickart. During the ten-day mission, they tested systems and procedures critical to landing on the Moon, including the LM engines, backpack life support systems, navigation systems and docking maneuvers.

After launching on March 3, 1969, the crew performed the first crewed flight of a lunar module, the first docking and extraction of the same, one two-person spacewalk (EVA), and the second docking of two crewed spacecrafttwo months after the Soviets performed a spacewalk crew transfer between Soyuz 4 and Soyuz 5. The mission concluded on March 13 and was a complete success. It proved the LM worthy of crewed spaceflight, setting the stage for the dress rehearsal for the lunar landing, Apollo 10, before the ultimate goal, landing on the Moon.

The Apollo program, also known as Project Apollo, was the third United States human spaceflight program carried out by the National Aeronautics and Space Administration (NASA), which succeeded in preparing and landing the first humans on the Moon from 1968 to 1972. It was first conceived during Dwight D. Eisenhower's administration as a three-person spacecraft to follow the one-person Project Mercury, which put the first Americans in space. Apollo was later dedicated to President John F. Kennedy's national goal for the 1960s of "landing a man on the Moon and returning him safely to the Earth" in an address to Congress on May 25, 1961. It was the third US human spaceflight program to fly, preceded by the two-person Project Gemini conceived in 1961 to extend spaceflight capability in support of Apollo.

Kennedy's goal was accomplished on the Apollo 11 mission when astronauts Neil Armstrong and Buzz Aldrin landed their Apollo Lunar Module (LM) on July 20, 1969, and walked on the lunar surface, while Michael Collins remained in lunar orbit in the command and service module (CSM), and all three landed safely on Earth on July 24. Five subsequent Apollo missions also landed astronauts on the Moon, the last, Apollo 17, in December 1972. In these six spaceflights, twelve people walked on the Moon.

Apollo ran from 1961 to 1972, with the first crewed flight in 1968. It encountered a major setback in 1967 when an Apollo 1 cabin fire killed the entire crew during a prelaunch test. After the first successful landing, sufficient flight hardware remained for nine follow-on landings with a plan for extended lunar geological and astrophysical exploration. Budget cuts forced the cancellation of three of these. Five of the remaining six missions achieved successful landings, but the Apollo 13 landing was prevented by an oxygen tank explosion in transit to the Moon, which destroyed the service module's capability to provide electrical power, crippling the CSM's propulsion and life support systems. The crew returned to Earth safely by using the lunar module as a "lifeboat" for these functions. Apollo used the Saturn family of rockets as launch vehicles, which were also used for an Apollo Applications Program, which consisted of Skylab, a space station that supported three crewed missions in 1973–1974, and the Apollo–Soyuz Test Project, a joint United States-Soviet Union low Earth orbit mission in 1975.

Apollo set several major human spaceflight milestones. It stands alone in sending crewed missions beyond low Earth orbit. Apollo 8 was the first crewed spacecraft to orbit another celestial body, and Apollo 11 was the first crewed spacecraft to land humans on one.

Overall the Apollo program returned 842 pounds (382 kg) of lunar rocks and soil to Earth, greatly contributing to the understanding of the Moon's composition and geological history. The program laid the foundation for NASA's subsequent human spaceflight capability, and funded construction of its Johnson Space Center and Kennedy Space Center. Apollo also spurred advances in many areas of technology incidental to rocketry and human spaceflight, including avionics, telecommunications, and computers.