Edward Stafford, 3rd Duke of Buckingham (3 February 1478 – 17 May 1521) was an English nobleman. He was the son of Henry Stafford, 2nd Duke of Buckingham, and Katherine Woodville, and nephew of Elizabeth Woodville and King Edward IV. Thus, Edward Stafford was a first cousin once removed of King Henry VIII. He was convicted of treason and executed on 17 May 1521.