Leslie O'Neal, American football player
Leslie Claudis O'Neal (born May 7, 1964) is an American former professional football player who was a defensive end and outside linebacker for 13 years in the National Football League (NFL). He spent the majority of his career with the San Diego Chargers before finishing with the St. Louis Rams and Kansas City Chiefs. He was a three-time All-Pro and six-time Pro Bowl selection during his pro career.

O'Neal was a two-time All-American playing college football with the Oklahoma State Cowboys. He joined the Chargers after they selected him in the first round with the eighth overall pick in the 1986 NFL draft. He was named NFL Defensive Rookie of the Year, but suffered a major knee injury at the end of his first season. He returned within two years, and finished his career as the Chargers all-time leader in sacks.