STS-2 was the second Space Shuttle mission conducted by NASA, and the second flight of the orbiter Columbia. The mission, crewed by Joe H. Engle and Richard H. Truly, launched on November 12, 1981, and landed two days later on November 14, 1981. STS-2 marked the first time that a crewed, reusable orbital vehicle returned to space. This mission tested the Shuttle Imaging Radar (SIR) as part of the OSTA-1 (Office of Space and Terrestrial Applications) payload, along with a wide range of other experiments including the Shuttle robotic arm, commonly known as Canadarm. Other experiments or tests included Shuttle Multispectral Infrared Radiometer, Feature Identification and Location Experiment, Measurement of Air Pollution from Satellites, Ocean Color Experiment, Night/Day optical Survey of Lightning, Heflex Bioengineering Test, and Aerodynamic Coefficient Identification Package (ACIP). One of the feats accomplished was various tests on the Orbital Maneuvring System (OMS) including starting and restarting the engines while in orbit and various adjustments to its orbit. The OMS tests also help adjust the Shuttle's orbit for use of the radar. During the mission, President Reagan called the crew of STS-2 from Mission Control Center in Houston.In the early planning stages of the Space Shuttle program, STS-2 was intended to be a reboost mission for the aging Skylab space station. However, such a mission was impeded by delays with the Shuttle's development and the deteriorating orbit of Skylab. Skylab ultimately de-orbited on July 11, 1979, two years before the launch of STS-2.

The Space Shuttle program was the fourth human spaceflight program carried out by the U.S. National Aeronautics and Space Administration (NASA), which accomplished routine transportation for Earth-to-orbit crew and cargo from 1981 to 2011. Its official name, Space Transportation System (STS), was taken from a 1969 plan for a system of reusable spacecraft of which it was the only item funded for development.The Space Shuttle—composed of an orbiter launched with two reusable solid rocket boosters and a disposable external fuel tank—carried up to eight astronauts and up to 50,000 lb (23,000 kg) of payload into low Earth orbit (LEO). When its mission was complete, the orbiter would reenter the Earth's atmosphere and land like a glider at either the Kennedy Space Center or Edwards Air Force Base.

The Shuttle is the only winged crewed spacecraft to have achieved orbit and landing, and the first reusable crewed space vehicle that has made multiple flights into orbit. Its missions involved carrying large payloads to various orbits including the International Space Station (ISS), providing crew rotation for the space station, and performing service missions on the Hubble Space Telescope. The orbiter also recovered satellites and other payloads (e.g., from the ISS) from orbit and returned them to Earth, though its use in this capacity was rare. Each vehicle was designed with a projected lifespan of 100 launches, or 10 years' operational life. Original selling points on the shuttles were over 150 launches over a 15-year operational span with a 'launch per month' expected at the peak of the program, but extensive delays in the development of the International Space Station never created such a peak demand for frequent flights.