The Dutch pacification campaign on Formosa was a series of military actions and diplomatic moves undertaken in 1635 and 1636 by Dutch East India Company (VOC) in Dutch-era Taiwan (Formosa) aimed at subduing hostile aboriginal villages in the southwestern region of the island. Prior to the campaign the Dutch had been in Formosa for eleven years, but did not control much of the island beyond their principal fortress at Tayouan (present-day Anping, Tainan), and an alliance with the town of Sinkan. The other aboriginal villages in the area conducted numerous attacks on the Dutch and their allies, with the chief belligerents being the village of Mattau, who in 1629 ambushed and slaughtered a group of sixty Dutch soldiers.

After receiving reinforcements from the colonial headquarters at Batavia, the Dutch launched an attack in 1635 and were able to crush opposition and bring the area around present-day Tainan fully under their control. After seeing Mattau and Soulang, the most powerful villages in the area, were overpowered by Dutch force overwhelmingly, many other villages in the surrounding area came to the Dutch to seek peace and surrender sovereignty. Thus the Dutch were able to dramatically expand the extent of their territorial control in a short time, and avoid the need for further fighting. The campaign ended in February 1636, when representatives from twenty-eight villages attended a ceremony in Tayouan to cement Dutch sovereignty.

Solidifying the southwest under their rule, the Dutch were able to expand their operations from the limited entrept trading carried out by the colony prior to 1635. The expanded territory allowed access to the deer trade, which later became very lucrative, and guaranteed security in food supplies. The new territorial acquisitions provided fertile land, which the Dutch began to import mass Chinese labours to farm. The aboriginal villages also provided warriors to aid the Dutch in times of trouble, notably in the Lamey Island Massacre of 1636, the Dutch defeat of the Spanish in 1642 and the Guo Huaiyi Rebellion in 1652. The allied villages also provided opportunities for Dutch missionaries to spread their faith. The pacification campaign is considered the foundation stone on which the later success of the colony was built.

The island of Taiwan, also commonly known as Formosa, was partly under colonial rule by the Dutch Republic from 1624 to 1662 and from 1664 to 1668. In the context of the Age of Discovery, the Dutch East India Company established its presence on Formosa to trade with the Ming Empire in neighbouring China and Tokugawa shogunate in Japan, and also to interdict Portuguese and Spanish trade and colonial activities in East Asia.

The Dutch were not universally welcomed, and uprisings by both aborigines and recent Han arrivals were quelled by the Dutch military on more than one occasion. With the rise of the Qing dynasty in the early 17th century, the Dutch East India Company cut ties with the Ming dynasty and allied with the Qing instead, in exchange for the right to unfettered access to their trade and shipping routes. The colonial period was brought to an end after the 1662 Siege of Fort Zeelandia by Koxinga's army who promptly dismantled the Dutch colony, expelled the Dutch and established the Ming loyalist, anti-Qing Kingdom of Tungning.