Hurricane Matthew was the first Category 5 Atlantic hurricane since Felix in 2007. Matthew caused catastrophic damage and a humanitarian crisis in Haiti, as well as widespread devastation in the southeastern United States. The deadliest Atlantic hurricane since Hurricane Stan in 2005, Matthew was the thirteenth named storm, fifth hurricane and second major hurricane of the 2016 Atlantic hurricane season. It caused extensive damage to landmasses in the Greater Antilles, and severe damage in several islands of the Bahamas which were still recovering from Joaquin, which had pounded the archipelago nearly a year earlier. Matthew also approached the southeastern United States, but stayed just offshore, paralleling the Florida coastline.

Originating from a tropical wave that emerged off Africa on September 22, Matthew developed into a tropical storm just east of the Lesser Antilles on September 28. It became a hurricane north of Venezuela and Colombia on September 29, before undergoing explosive intensification, ultimately reaching Category 5 intensity on October 1 with peak 1-minute sustained winds of 165 mph. This strength was attained at just 13.4°N latitude – the lowest latitude ever recorded for a storm of this intensity in the Atlantic basin, breaking the record set by Hurricane Ivan in 2004. Matthew weakened slightly and fluctuated in intensity while making a northward turn toward the Greater Antilles, remaining a strong Category 4 hurricane as it made its first landfall over Haiti's Tiburon Peninsula early on October 4, and then a second one in Cuba later that day. Matthew weakened somewhat but re-intensified as it tracked northwest, making landfall in the northern Bahamas. The storm then paralleled the coast of the southeastern United States over the next 36 hours, gradually weakening while remaining just offshore before making its fourth and final landfall over the Cape Romain National Wildlife Refuge near McClellanville, South Carolina as a Category 1 hurricane on the morning of October 8. Matthew re-emerged into the Atlantic shortly afterward, eventually completing its transition into an extratropical cyclone as it turned away from Cape Hatteras, North Carolina on October 9. The remnants of Matthew continued to accelerate towards Canada where it was absorbed by a cold front.Widespread effects were felt from Matthew across its destructive path, however, the most significant impacts were felt in Haiti, with US$2.8 billion in damage and 546 deaths, making Matthew the worst disaster to affect the nation since the 2010 earthquake. The combination of flooding and high winds disrupted telecommunications and destroyed extensive swaths of land; around 80% of Jérémie sustained significant damage. Four people were killed in Cuba due to a bridge collapse, and total losses in the country amounted to US$2.58 billion, most of which occurred in the Guantánamo Province. Passing through the Bahamas as a major hurricane, Matthew spread damage across several islands. Grand Bahama was hit directly, where most homes sustained damage in the townships of Eight Mile Rock and Holmes Rock. Preparations began in earnest across the southeastern United States as Matthew approached, with several states declaring states of emergencies for either entire states or coastal counties; widespread evacuations were ordered for extensive areas of the coast because of predicted high wind speeds and flooding, especially in the Jacksonville Metropolitan Area. In Florida, over 1 million lost power as the storm passed to the east, with 478,000 losing power in Georgia and South Carolina. While damage was primarily confined to the coast in Florida and Georgia, torrential rains spread inland in the Carolinas and Virginia, causing widespread flooding.