The Siege of Tripolitsa, also known as the Fall of Tripolitsa (Greek: Άλωση της Τριπολιτσάς, romanized: Álosi tis Tripolitsás, Greek pronunciation: [ˈalosi tis tripoliˈt͡sas]) and in Turkish sources as the Tripolitsa Massacre (Turkish: Tripoliçe Katliamı), was an early victory of the revolutionary Greek forces in the summer of 1821 during the Greek War of Independence, which had begun earlier that year, against the Ottoman Empire. Tripolitsa was an important target, because it was the administrative center of the Ottomans in the Peloponnese.

Following the capture of the city by the Greek revolutionary forces, a massacre of its population occurred.