Pacific Southwest Airlines (PSA) Flight 182 was a Boeing 727-214 commercial airliner, registration N533PS, that collided with a private Cessna 172 light aircraft, registration N7711G, over San Diego, California, at 9:01 am on Monday, September 25, 1978. It was Pacific Southwest Airlines' first fatal accident, and the deadliest air disaster in California history.

Both aircraft crashed into North Park, a San Diego neighborhood. Flight 182 impacted just north of the intersection of Dwight and Nile streets, killing all 135 people aboard the aircraft and seven people on the ground in houses, including two children. The Cessna impacted Polk Avenue between 32nd and Iowa streets, killing the two on board. Nine others on the ground were injured and twenty-two homes were destroyed or damaged by the impact and debris.